Folic Acid, Vitamin B12 and Nucleic Acid Synthesis in Lactobacillus casei

The influence of folic acid and vitamin B12 on nucleic acid metabolism in microorganisms.

A combination of purines and thymine has long been known to substitute for folic acid (FA) in the nutrition of microorganisms requiring the vitamin. The purines were found to be interchangeable, but the effect of thymine was specific and could only be duplicated by its desoxyriboside, thymidine (l-4). From these and other studies on inhibition analysis (5, S), it was concluded that the purines ...

The activity of Lactobacillus casei factor, folic acid, and vitamin Bc for Streptococcus faecalis and Lactobacillus casei.

It has been established that the terms vitamin M, vitamin B,, norit eluate factor, Lactobacillus casei factor, factor U, folic acid, and factor SLR all refer to a group of compounds (or a compound) with similar characteristics and similar biological activities. Of these factors seven have been reported in purified form: folic acid (isolated from spinach) (l), three L. casei factors (one from li...

PREVENTIVE EFFECTS OF VITAMIN B12 AND FOLIC ACID IN METHANOL-INDUCED RETINOPATHY IN AN ANIMAL MODEL

In order to identify the effects of vitamin B 12 and folic acid in reducing methanolinduced retinopathy, ERG waves were compared before and after methanol intoxication in rabbits. In this study 34 rabbits were divided into 4 groups. All groups received 4 g/kg of methanol intraperitoneally. In addition, the second, third and fourth groups received vitamin B 12 injection, oral folic acid and ...

Serum folic-acid and vitamin-B12 levels in anticonvulsant therapy.

Serum Levels of Homocysteine, Vitamin B12, and Folic Acid in Patients with Alzheimer’s Disease

Background: Alzheimer's disease is the most common form of dementia in the elderly. Serum levels of homocysteine have been related to increased cortical and hippocampal atrophy. We aimed to determine the serum levels of homocysteine, folate, and vitamin B12 in patients with Alzheimer's disease. Methods: Blood levels of homocysteine and its biological determinants, folate, and vitamin B12 were m...